Premedication with pronase or N-acetylcysteine improves visibility during gastroendoscopy: an endoscopist-blinded, prospective, randomized study.

  title={Premedication with pronase or N-acetylcysteine improves visibility during gastroendoscopy: an endoscopist-blinded, prospective, randomized study.},
  author={Chun-Chao Chang and Sheng-Hsuan Chen and Chih-Ping Lin and Ching-Ruey Hsieh and Horng-Yuan Lou and Fat‐Moon Suk and Shiann Pan and Mingfeng Wu and Jun-Nan Chen and Yung-fa Chen},
  journal={World journal of gastroenterology},
  volume={13 3},
AIM To assess the efficacy of premedicaton with pronase or N-acetylcysteine (NAC) at 20 min before upper gastrointestinal (UGI) endoscopy and to determine whether pronase or NAC pretreatment influences the reliability of the rapid urease test. METHODS A total of 146 patients were prospectively and randomly assigned into the study groups according to different premedications before endoscopy. One endoscopist assessed mucosal visibility (MV) with scores ranged from 1 to 4 at four sites in the… 

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