Premedication with nasal s-ketamine and midazolam provides good conditions for induction of anesthesia in preschool children.

@article{Weber2003PremedicationWN,
  title={Premedication with nasal s-ketamine and midazolam provides good conditions for induction of anesthesia in preschool children.},
  author={Frank S Weber and Hinnerk F. Wulf and Ghada el Saeidi},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={2003},
  volume={50 5},
  pages={470-5}
}
PURPOSE To evaluate the efficacy and safety of intranasally administered s-ketamine and midazolam for premedication in pediatric patients. METHODS Ninety children were randomly allocated to receive intranasally administered s-ketamine 1 mg.kg(-1) and midazolam 0.2 mg.kg(-1) (Group K1, n = 30), s-ketamine 2 mg.kg(-1) and midazolam 0.2 mg.kg(-1) (Group K2, n = 30), or midazolam 0.2 mg.kg(-1) (Group M, n = 30) as premedicants, using a double-blind study design. Sedation and anxiolysis were… CONTINUE READING