Premedication with famotidine augments core hypothermia during general anesthesia.

@article{Hirose1995PremedicationWF,
  title={Premedication with famotidine augments core hypothermia during general anesthesia.},
  author={Munetaka Hirose and Yasufumi Hara and M Matsusaki},
  journal={Anesthesiology},
  year={1995},
  volume={83 6},
  pages={
          1179-83
        }
}
BACKGROUND Animal studies have provided considerable evidence to support a role of histamine in the central nervous system in thermoregulation, and premedication with a histamine H2 receptor antagonist before general anesthesia is used to reduce the risk of acid aspiration. The authors investigated whether premedication with famotidine had an effect on thermoregulation during general anesthesia. METHODS In a randomized, placebo-controlled study, 30 ASA physical status 1 or 2 patients… CONTINUE READING

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  • 2002