Premature release of Plasmodium falciparum from swollen erythrocytes induced by some antimalarials.

@article{Gu1989PrematureRO,
  title={Premature release of Plasmodium falciparum from swollen erythrocytes induced by some antimalarials.},
  author={H. Gu and J. Inselburg},
  journal={The Journal of parasitology},
  year={1989},
  volume={75 1},
  pages={
          153-7
        }
}
Qinghaosu and chloroquine, but not pyrimethamine, treatment of Plasmodium falciparum cultures resulted in the formation of swollen red blood cells (RBCs) and the expulsion of degenerate trophozoites and schizonts, but not ring-stage parasites, from the infected RBCs. The parasite release resulted in the formation of RBCs with holes, that had otherwise retained their structural integrity. Membranes of swollen RBCs and their ghosts associated with parasites were efficiently visualized by Giemsa… Expand
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