Premature ovarian failure due to cyclophosphamide: a report of four cases in dermatology practice.

@article{Saoji2008PrematureOF,
  title={Premature ovarian failure due to cyclophosphamide: a report of four cases in dermatology practice.},
  author={Vikrant A Saoji},
  journal={Indian journal of dermatology, venereology and leprology},
  year={2008},
  volume={74 2},
  pages={128-32}
}
  • Vikrant A Saoji
  • Published 2008 in
    Indian journal of dermatology, venereology and…
Immunosuppressant drugs like cyclophosphamide are used in the treatment of a variety of skin disorders. Though it is a very useful drug, it has some serious side-effects. Prolonged amenorrhea due to premature ovarian failure leading to infertility is one of the serious side-effects of cyclophosphamide. Four cases of cyclophosphamide-induced premature ovarian failure are presented. Two patients of scleroderma, one patient of pemphigus and one patient of hypersensitivity vasculitis developed… CONTINUE READING

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