Premature ovarian failure: steroid synthesis and autoimmunity.

  title={Premature ovarian failure: steroid synthesis and autoimmunity.},
  author={Nicola Doldi and Laura Belvisi and Marianna Bassan and Francesco Maria Fusi and Augusto Ferrari},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  volume={12 1},
The androgen biosynthesis and autoimmunity of 25 patients with premature ovarian failure (POF) and 18 control subjects with normal cycles were examined. Serum levels of dehydroepiandrosterone sulfate (DHEAS), 17-hydroxyprogesterone (17-OHP), androstenedione, and testosterone were analyzed in POF patients with or without organ-specific autoimmunity, and the results compared with those of women with normal ovarian function. The comparative analysis of DHEAS, 17-OHP, androstenedione and… CONTINUE READING
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