Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

Abstract

In vertebrates, skeletal myogenesis is initiated by the generation of myoblasts followed by their differentiation to myocytes and the formation of myofibers. The determination of myoblasts and their differentiation are controlled by muscle regulatory factors that are activated at specific stages during myogenesis. During late embryonic and fetal stages a… (More)

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@article{SchusterGossler2007PrematureMD, title={Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.}, author={Karin Schuster-Gossler and Ralf Cordes and Achim Gossler}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2007}, volume={104 2}, pages={537-42} }