Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study.

@article{Sklar2006PrematureMI,
  title={Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study.},
  author={Charles A. Sklar and Ann C Mertens and Pauline A Mitby and John A. Whitton and Marilyn S. Stovall and Catherine Grey Kasper and Jean Mulder and Daniel M. Green and Helen S. Nicholson and Yutaka Yasui and Leslie L. Robison},
  journal={Journal of the National Cancer Institute},
  year={2006},
  volume={98 13},
  pages={
          890-6
        }
}
BACKGROUND Childhood cancer survivors who retain ovarian function after completing cancer treatment are at increased risk of developing premature menopause, defined as cessation of menses before age 40 years. However, published data pertaining to the risk and frequency of premature menopause are limited. METHODS We assessed the incidence of and risk factors for premature menopause in 2819 survivors of childhood cancer who were older than 18 years and were participants in the multicenter… CONTINUE READING

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