Premature estrogen exposure alters endometrial gene expression to disrupt pregnancy in the pig.

@article{Ross2007PrematureEE,
  title={Premature estrogen exposure alters endometrial gene expression to disrupt pregnancy in the pig.},
  author={Jason W Ross and Morgan D Ashworth and Frankie J White and Gregory A. Johnson and Patricia J Ayoubi and Udaya Desilva and Kristin M Whitworth and Randall S Prather and Rodney D Geisert},
  journal={Endocrinology},
  year={2007},
  volume={148 10},
  pages={4761-73}
}
Establishment and maintenance of pregnancy in the pig involve intricate communication between the developing conceptuses and maternal endometrium. Conceptus synthesis and release of estrogen during trophoblastic elongation are essential factors involved with establishing conceptus-uterine communication. The present study identified endometrial changes in gene expression associated with implantation failure and complete pregnancy loss after premature exposure of pregnant gilts to exogenous… CONTINUE READING

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