Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene.

@article{Benlian1996PrematureAI,
  title={Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene.},
  author={Pascale Benlian and J-L de Gennes and Luc Foubert and He Zhang and Suzie Gagn{\'e} and Michael R. Hayden},
  journal={The New England journal of medicine},
  year={1996},
  volume={335 12},
  pages={848-54}
}
BACKGROUND Patients with lipoprotein lipase deficiency usually present with chylomicronemia in childhood. The syndrome has been considered nonatherogenic primarily because of the low levels of low-density lipoprotein (LDL) cholesterol. We prospectively evaluated patients with lipoprotein lipase deficiency for atherosclerosis. METHODS Evidence of carotid, peripheral, and coronary atherosclerosis was sought in four patients (two men and two women) with the phenotype of familial chylomicronemia… CONTINUE READING