Premature Ovarian Failure: A Critical Condition in The Reproductive Potential with Various Genetic Causes

@inproceedings{Pouresmaeili2014PrematureOF,
  title={Premature Ovarian Failure: A Critical Condition
in The Reproductive Potential with
Various Genetic Causes},
  author={Farkhondeh Pouresmaeili and Zahra Fazeli},
  booktitle={International journal of fertility & sterility},
  year={2014}
}
Premature ovarian failure (POF) is identified as a heterogeneous disorder leading to amenorrhea and ovarian failure before the age of 40 years. The first known symptom of the disease is having irregular menstrual periods. The phenotype appearance of POF depends significantly on the variations in hormones. Low levels of gonadal hormones (estrogens and inhibins) and increased level of gonadotropins [luteinizing hormone (LH) and Follicle stimulating hormone (FSH)] (hypergonadotropic amenorrhea… CONTINUE READING