Premature Menopause in Patients with BRCA1 Gene Mutation

  title={Premature Menopause in Patients with BRCA1 Gene Mutation},
  author={I. Rzepka-g{\'o}rska and B. Tarnowski and A. Chudecka-Głaz and B. G{\'o}rski and D. Zielińska and A. Tołoczko-Grabarek},
  journal={Breast Cancer Research and Treatment},
  • I. Rzepka-górska, B. Tarnowski, +3 authors A. Tołoczko-Grabarek
  • Published 2006
  • Biology, Medicine
  • Breast Cancer Research and Treatment
  • This study was undertaken with regard to the gonadotropin theory of ovarian cancer advocated in the literature and was designed to disclose specific features of ovarian morphology in carriers of the BRCA1 gene mutation. We enrolled 171 patients and divided them into two groups: A (n=90)—operated for breast cancer (30 patients with and 60 without the BRCA1 mutation); B (n=81)—with the BRCA1 mutation qualified for preventive adnexectomy. According to the authors’ classification described herein… CONTINUE READING
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