Premalignant lesions of hepatocellular carcinoma: pathologic viewpoint.

  • Masumi Kojiro
  • Published 2000 in Journal of hepato-biliary-pancreatic surgery


The significance of large cell dysplasia and small cell dysplasia as premalignant lesions has been extensively discussed. At present the majority of researchers consider that the former seems to be a secondary change rather than a premalignant lesion, and the latter is strongly suggested to be a premalignant lesion. In the past decade, however, adenomatous… (More)


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