• Corpus ID: 89297824

Preliminary tests of antiviral activity of two Inonotus obliquus strains.

  title={Preliminary tests of antiviral activity of two Inonotus obliquus strains.},
  author={Kirsti Kahlos and Anna Lesnau and Wouter Lange and Ulrike Lindequist},
Tests of the antiviral activity of I. obliquus grown in alder and birch was carried out against human influenza viruses A and B and horse influenza viruses A (strains A/H1N1, A/H3N2, A/Equine2, B/Yamagata/16/18). The black, thin external surface of fungus grown in birch had complete inhibition (100%) against all influenza viruses. The antiviral activity is thought to be mainly due to betulin, lupeol and mycosterols. 

Progress of research on Inonotus obliquus

The biological characteristics, chemical composition and pharmacologic effects of Inonotus obliquus, especially in treating malignant tumors, diabetes, cardiovascular disease and AIDS, and the applications in medicine and food were introduced.


A review of previously published literature about this fungus is made, dealing with its ethnomycological, nutritional, pharmacological and medical aspects.

Chemical diversity of biologically active metabolites in the sclerotia of Inonotus obliquus and submerged culture strategies for up-regulating their production

This review examines the current progress in the discovery of chemical diversity of Chaga and their biological activities and the strategies to modulate the expression of desired pathways to diversify and up-regulate the production of bioactive metabolites by the fungus grown in submerged cultures for possible drug discovery.

Review of Medicinal Uses of Chaga ( Inonotus obliquus )

The name Chaga originated in Siberia and is derived from the name for mushroom in the Komi-Permyak language, which is spoken by natives of the Kama River Basin in the West Uralian region.

차가버섯 균사체로부터 단백다당체의 추출 공정 확립

Inonotus obliquus mushroom, which is a fungus belonging to Hymenochaetaceae family, is known to grow on birth trees in colder northern climates and to be a fungal parasite that draws nutrients out of

Chemical constituents ofInonotus obliquus II: a new triterpene, 21,24-cyclopentalanosta-3β,21,25-triol-8-ene from sclerotium

A new lanostane-type triterpene with a cyclopentanol partial structure in the side chain was isolated from the sclerotium of the wood rotting fungusInonotus obliquus along with four known compounds:

Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay

Chaga mushroom treatment affords cellular protection against endogenous DNA damage produced by H2O2, and shows over 40% reduction in DNA fragmentation compared with the positive control.

Exploring Mushroom Diversity for Pharmaceutical Utility

A large number of mushroom species including Ganoderma lucidum, Coriolus versicolor, Fomes fometarius, Tremella fuciformis and Lentinus edodes are traditionally used in Chinese folk medicines and are being explored extensively for their pharmaceutical utility.

Gamma-irradiation improves the color and antioxidant properties of Chaga mushroom (Inonotus obliquus) extract.

It is suggested that gamma-irradiation could be considered a means for improving the antioxidant properties and the color of CME.