Preliminary studies on a more effective phototoxic agent than hematoporphyrin.

Abstract

Phototoxicity of benzoporphyrin derivative (BPD) has been tested in vitro and compared with that of hematoporphyrin (HP). After 1-hour activation with visible light, BPD was 10 times more cytotoxic than HP toward human adherent cell lines: A549 lung cancer, Calu-1 lung carcinoma, and CCD-19Lu normal lung, killing 100% of cells at the concentration of 70 ng… (More)

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@article{Richter1987PreliminarySO, title={Preliminary studies on a more effective phototoxic agent than hematoporphyrin.}, author={Anna M. Richter and Barbara Kelly and Jeffrey C F Chow and Diana J Liu and G. H. Neil Towers and David H. Dolphin and Julia G. Levy}, journal={Journal of the National Cancer Institute}, year={1987}, volume={79 6}, pages={1327-32} }