Preliminary results of a double-blind, randomized, placebo-controlled trial of cyclosporine in myasthenia gravis.

@article{Tindall1987PreliminaryRO,
  title={Preliminary results of a double-blind, randomized, placebo-controlled trial of cyclosporine in myasthenia gravis.},
  author={R S Tindall and Judy Ann Rollins and J. Theodore Phillips and Ross Greenlee and Leigh Wells and G Belendiuk},
  journal={The New England journal of medicine},
  year={1987},
  volume={316 12},
  pages={719-24}
}
We randomly assigned 20 patients with progressively worsening generalized myasthenia gravis of recent onset whose illness was not controlled by anticholinesterase therapy to treatment with either cyclosporine (6 mg per kilogram of body weight per day) or placebo. Patients who had been treated with thymectomy, steroids, or other immunosuppressive agents were excluded. The duration of treatment was 12 months. Disease activity was assessed by quantified strength testing and by measurements of… CONTINUE READING
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