Preliminary report of the Asian-Oceanian Clinical Oncology Association randomized trial comparing cisplatin and epirubicin followed by radiotherapy versus radiotherapy alone in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Asian-Oceanian Clinical Oncology Associati

@article{Chua1998PreliminaryRO,
  title={Preliminary report of the Asian-Oceanian Clinical Oncology Association randomized trial comparing cisplatin and epirubicin followed by radiotherapy versus radiotherapy alone in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Asian-Oceanian Clinical Oncology Associati},
  author={Daniel T T Chua and Jonathan Shun-Tong Sham and Damon Choy and Vicharn Lorvidhaya and Yupa Sumitsawan and Sumitra Thongprasert and Visoot Vootiprux and Arkom Cheirsilpa and T Azhar and Ary Harryanto Reksodiputro},
  journal={Cancer},
  year={1998},
  volume={83 11},
  pages={2270-83}
}
BACKGROUND The aim of this trial was to compare the outcome achieved with neoadjuvant chemotherapy followed by radiotherapy to that achieved with radiotherapy alone for patients with locoregionally advanced undifferentiated or poorly differentiated nasopharyngeal carcinoma (NPC) meeting one of the following criteria: Ho's T3 disease, Ho's N2-N3 disease, or lymph node size > or =3 cm. METHODS Between September 1989 and August 1993, 334 patients were enrolled in the study, with equal numbers of… CONTINUE READING

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