Preliminary report of a longitudinal study of the effects of lithium on iodine metabolism.
@article{Tb1969PreliminaryRO, title={Preliminary report of a longitudinal study of the effects of lithium on iodine metabolism.}, author={Cooper Tb and Simpson Gm}, journal={Current Therapeutic Research-clinical and Experimental}, year={1969}, volume={11}, pages={603} }
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29 Citations
The Use of Lithium as an Adjuvant to Radioiodine in the Treatment of Thyroid Cancer
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Lithium ion, administered as the carbonate salt, blocks thyrocyte release of 131I incorporated in thyroid hormone and is the most promising method to enhance the radiation dose to tumors and improve the therapeutic effectiveness of radioiodine.
Use of Lithium as an Adjuvant to Radioiodine in the Treatment of Thyroid Cancer
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To optimize radionuclide uptake, dietary depletion of iodide and thyrotropin-secreting hormone- induced sodium-iodide symporter activity are required to enhance the half-time of 131I in the tumor tissue.
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The inhibitory action of lithium chloride on hormone production in the thyroid gland and on the secretion of thyroid hormones into the blood stream was shown to be directly dependent on the dose of the compound and the lithium concentration in the blood.
Thyroid abnormalities during lithium treatment
- Medicine, PsychologyActa psychiatrica Scandinavica
- 1991
Thyroid function was evaluated in 150 Sardinian outpatients at different stages of lithium treatment, and the prevalence of specific antithyroid antibodies was positively correlated with age and duration of lithium Treatment, and was higher in women.
Antinuclear Antibodies and Antithyroid Antibodies in Psychiatric Patients
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- 1987
Data from a series of studies to determine whether antibodies against brain tissue were present in patients with schizophrenia suggest that although certain abnormal autoimmune phenomena are seen with use of certain psychotropic agents, they rarely impact on clinical care.
Effect of Lithium on the Thyroid Gland
- Medicine, Psychology
- 1986
A large volume of basic and clinical research has been performed to establish the pathophysiology of the action of lithium on the thyroid gland and the clinical relevance of the effects of lithium in patients receiving lithium therapy and patients with thyroid disease.
The effect of rubidium and lithium on adenylate cyclase and neurotransmitter receptors
- Biology
- 1984
This paper will compare lithium (Li) and rubidium (Rb) effects in the context of two current theories of Li action: 1) Inhibition of nora-drenaline (NA)-sensitive adenylate cyclase, and 2)…