Preliminary observations on possible premalignant changes in bone marrow adjacent to worn total hip arthroplasty implants.

@article{Case1996PreliminaryOO,
  title={Preliminary observations on possible premalignant changes in bone marrow adjacent to worn total hip arthroplasty implants.},
  author={Charles Patrick Case and Victor G Langkamer and Rodney Howell and Jill J. Webb and Graham Standen and Martin Palmer and Andrew Kemp and Ian Douglas Learmonth},
  journal={Clinical orthopaedics and related research},
  year={1996},
  volume={329 Suppl},
  pages={S269-79}
}
Previous epidemiologic studies have suggested that there may be a risk of malignancy, especially lymphoma and leukemia, after joint replacement, but the followup has been relatively short. This is a preliminary study to see if there is any biologic basis for such a risk. Blood and bone marrow samples from 71 patients at revision arthroplasty of a loose or worn prosthesis and 30 control patients at primary arthroplasty were analyzed with cytogenetic techniques and molecular biology. There was a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…