Preliminary in situ identification of estrogen target cells in bone.

  title={Preliminary in situ identification of estrogen target cells in bone.},
  author={Isobel Braidman and Laura Davenport and Duncan Howard Carter and Peter Selby and E. Barbara Mawer and Anthony John Freemont},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  volume={10 1},
Although estrogens profoundly influence skeletal growth and maturation, their mechanism of action is still unclear. To identify their target cells in bone, estrogen receptors were located by immunofluorescence using the H222 monoclonal antibody in cryosections (both undecalcified and briefly decalcified) of hyperplastic mandibular condyle (persistent asymmetric mandibular growth) from a 14-year-old girl and radius and ulna from an 18-month-old female pig (epiphyseal fusion) and from a 3-month… CONTINUE READING
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