Preliminary experiences with a single-patient trials service in general practice.

@article{Nikles2000PreliminaryEW,
  title={Preliminary experiences with a single-patient trials service in general practice.},
  author={Catherine Jane Nikles and Paul Glasziou and Chris Del Mar and Colette M Duggan and Alexandra Marie Clavarino and Michael J. Yelland},
  journal={The Medical journal of Australia},
  year={2000},
  volume={173 2},
  pages={100-3}
}
OBJECTIVE To pilot a single-patient trials (SPTs) service in general practice, designed to improve decision-making about long-term medications for chronic conditions. DESIGN 12-week within-patient, randomised, double-blind, placebo-controlled, crossover comparison of ibuprofen with paracetamol for osteoarthritis, involving three pairs of two-week treatment periods for each participating patient. SETTING AND PATIENTS Patients attending an academic general practice with a clinical diagnosis… CONTINUE READING
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