Preliminary experience with use of a selective 5HT3 receptor antagonist (ondansetron) to prevent high dose chemotherapy induced emesis.

@article{Parikh1996PreliminaryEW,
  title={Preliminary experience with use of a selective 5HT3 receptor antagonist (ondansetron) to prevent high dose chemotherapy induced emesis.},
  author={Purvish Mahendra Parikh and Shailen R Shah and Sharad C Shah and Vaidehi Sheth and Roopal A Patel and Kirtida C Shah and Prashant K. Jain},
  journal={Indian journal of cancer},
  year={1996},
  volume={33 1},
  pages={17-20}
}
Ondansetron was used as an antiemetic along with dexamethasone during 16 cycles of highly or moderately ematogenic chemotherapy. There was major control in two cycles and complete control in the remaining 14. Side effects were minor and did not require discontinuation of the drug. This combination, therefore, appears to be safe and effective in preventing chemotherapy induced emesis. 

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