Preliminary associations between motor procedural learning, basal ganglia T2 relaxation times, and tardive dyskinesia in schizophrenia.

@article{Granholm1993PreliminaryAB,
  title={Preliminary associations between motor procedural learning, basal ganglia T2 relaxation times, and tardive dyskinesia in schizophrenia.},
  author={Eric L. Granholm and George Bartzokis and Robert F. Asarnow and Stephen R Marder},
  journal={Psychiatry research},
  year={1993},
  volume={50 1},
  pages={
          33-44
        }
}
The hypothesis that the caudate nucleus is involved in the pathophysiology of tardive dyskinesia (TD) in schizophrenia was investigated by examining motor procedural learning on the pursuit rotor task and basal ganglia T2 relaxation times (T2) determined using magnetic resonance imaging (MRI). Increased severity of TD was associated with shortened caudate T2 and decreased motor learning. Motor-learning scores of schizophrenic patients with and without TD did not differ significantly from those… CONTINUE READING