Preliminary application of magnetic resonance spectroscopy to investigate lactate-induced panic.

@article{Dager1994PreliminaryAO,
  title={Preliminary application of magnetic resonance spectroscopy to investigate lactate-induced panic.},
  author={Stephen R Dager and Kenneth I. Marro and Todd L. Richards and Giesela Metzger},
  journal={The American journal of psychiatry},
  year={1994},
  volume={151 1},
  pages={57-63}
}
OBJECTIVE To characterize changes associated with lactate-induced panic, proton magnetic resonance spectroscopy (MRS) was used to measure brain lactate during intravenous infusion of 0.5-M sodium lactate in panic disorder patients and comparison subjects. METHOD Eight panic disorder subjects, five medicated and three unmedicated, and eight healthy comparison subjects were studied at baseline, during lactate infusion (5 meq/kg over 20 minutes), and after infusion. Localized proton MRS was used… CONTINUE READING

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