Preliminary X-ray crystallographic analysis of the catalytic domain of prophenoloxidase activating factor-I.

@article{Piao2006PreliminaryXC,
  title={Preliminary X-ray crystallographic analysis of the catalytic domain of prophenoloxidase activating factor-I.},
  author={Shunfu Piao and Ji Young Jung and Ji Won Park and Jaewon Lee and Bok Leul Lee and Nam Chul Ha},
  journal={Acta crystallographica. Section F, Structural biology and crystallization communications},
  year={2006},
  volume={62 Pt 8},
  pages={771-3}
}
Clip-domain serine proteases (SPs) have been identified in invertebrates as crucial enzymes that are involved in diverse extracellular signalling pathways. Prophenoloxidase (proPO) activating factor-I (PPAF-I), a catalytically active clip-domain SP, cleaves proPO. To date, no crystal structures of a catalytically active clip-domain SP have been determined. Here, the results of crystallization and preliminary X-ray analysis of the SP domain of PPAF-I are reported. The crystal of the PPAF-I SP… CONTINUE READING
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