Preimplantation genetic diagnosis of numerical and structural chromosome abnormalities.

@article{Munn2002PreimplantationGD,
  title={Preimplantation genetic diagnosis of numerical and structural chromosome abnormalities.},
  author={Santiago Munn{\'e}},
  journal={Reproductive biomedicine online},
  year={2002},
  volume={4 2},
  pages={
          183-96
        }
}
The causes of the decline in implantation rates observed with increasing maternal age are still a matter for debate. Data from oocyte donation strongly suggest that in women of advanced reproductive age, the ability to become pregnant is largely unaffected while oocyte quality is compromised. The incidence of chromosomal abnormalities in embryos is considerably higher than that reported in spontaneous abortions, suggesting that a sizable percentage of chromosomally abnormal embryos are… CONTINUE READING
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