Preimplantation genetic diagnosis of aneuploidy and male infertility.

  title={Preimplantation genetic diagnosis of aneuploidy and male infertility.},
  author={Luca Gianaroli and Santiago Munn{\'e} and Maria Cristina Magli and Anna Pia Ferraretti},
  journal={International journal of andrology},
  volume={20 Suppl 3},
Preimplantation genetic diagnosis (PGD) of aneuploidy was performed on 49 patients diagnosed with severe male factor infertility and a poor prognosis of pregnancy due to: 1) advanced maternal age; 2) repeated IVF failures; and 3) altered karyotype in peripheral blood. The results attained were compared to those derived from 28 normospermic patients presenting the same poor prognostic indications. In all, 445 embryos were selected for fluorescent in-situ hybridization (FISH) analysis on the… CONTINUE READING
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