Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial.

@article{Cooper2004PrehospitalHS,
  title={Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial.},
  author={David Jamie Cooper and Paul S. Myles and Francis T Mcdermott and Lynette J Murray and John Laidlaw and Gregory Cooper and Ann B Tremayne and Stephen S Bernard and Jennie Louise Ponsford},
  journal={JAMA},
  year={2004},
  volume={291 11},
  pages={1350-7}
}
CONTEXT Prehospital hypertonic saline (HTS) resuscitation of patients with traumatic brain injury (TBI) may increase survival but whether HTS improves neurological outcomes is unknown. OBJECTIVE To determine whether prehospital resuscitation with intravenous HTS improves long-term neurological outcome in patients with severe TBI compared with resuscitation with conventional fluids. DESIGN, SETTING, AND PATIENTS Double-blind, randomized controlled trial of 229 patients with TBI who were… CONTINUE READING
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of Health

  • US National Institute
  • Rehabilitation of persons with traumatic brain…
  • 2004
Highly Influential
5 Excerpts

Hypertonic solutions: an update. In: Trauma Care: Journal of the International Trauma Anaesthesia and Critical Care Society

  • CH Svensen
  • ITACCS World Headquarters;
  • 2002
Highly Influential
7 Excerpts

Guidelines for the Pre-Hospital Management of Traumatic Brain Injury

  • EJ Gabriel, J Ghajar, A Jogada, PT Pons, T. Scalea
  • 2000
Highly Influential
7 Excerpts

Albumin reviewers: human albumin administration in critically ill patients: systematic review of randomised controlled trials

  • Cochrane Injuries Group
  • 1998
Highly Influential
5 Excerpts

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