Prehepatic portal hypertension worsens the enterohepatic redox balance in thioacetamide-cirrhotic rats.

Abstract

BACKGROUND Oxidative stress has been reported as a key pathogenic factor in many human liver diseases and in experimental models of cirrhosis related to hepatotoxin administration. The aim of this study was to verify the hypothesis that prehepatic portal hypertension aggravates the enterohepatic redox imbalance in thioacetamide-cirrhotic rats. MATERIALS… (More)
DOI: 10.1016/j.pathophys.2008.09.003

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