Pregnancy-specific b-1-glycoprotein 1 and human leukocyte antigen-E mRNA in human sperm : differential expression in fertile and infertile men and evidence of a possible functional role during early development

@inproceedings{Avendao2009PregnancyspecificB1,
  title={Pregnancy-specific b-1-glycoprotein 1 and human leukocyte antigen-E mRNA in human sperm : differential expression in fertile and infertile men and evidence of a possible functional role during early development},
  author={Conrado Avenda{\~n}o and Anahı́ Franchi and Estella Jones and Sergio Carlos Oehninger},
  year={2009}
}
background: Mature spermatozoa contain thousands of mRNA transcripts. It has been recently shown that human sperm can deliver RNA into the oocyte, suggesting that mRNAs might have a role before or after fertilization. Human embryos express PSG1 (pregnancyspecific b-1-glycoprotein 1) and HLA-E (human leukocyte antigen-E), molecules playing a role in implantation and early development. We compared PSG1 and HLA-E sperm mRNA levels in fertile and infertile men and we tested the hypothesis that… CONTINUE READING

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