Pregnancy-related steroids are potential negative regulators of B lymphopoiesis.


B lymphopoiesis is selectively suppressed in normal pregnant mice, suggesting that fluctuations in systemic hormone levels might influence local events within bone marrow. This has now been tested by sustained experimental elevation of sex steroids by hormone-containing pellet implants. We found that while numbers of total nucleated cells declined after… (More)


Cite this paper

@article{Medina1994PregnancyrelatedSA, title={Pregnancy-related steroids are potential negative regulators of B lymphopoiesis.}, author={Kay L. Medina and Paul W. Kincade}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1994}, volume={91 12}, pages={5382-6} }