Pregnancy outcomes following systemic prenatal acyclovir exposure--June 1, 1984-June 30, 1993.

  • Published 1993 in MMWR. Morbidity and mortality weekly report


Herpes infections are common among women of reproductive age (i.e., aged 15-44 years). Acyclovir (Zovirax), an antiviral drug effective in the treatment of herpes simplex infection, was approved by the Food and Drug Administration (FDA) in 1984. Since its approval, the effects of acyclovir on human pregnancies have not been determined. However, inadvertent… (More)


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