Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study
@article{Coelho2010PregnancyOI, title={Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study}, author={Jessica Coelho and Laurent Beaugerie and J F Colombel and Xavier H{\'e}buterne and {\'E}ric Lerebours and Marc L{\'e}mann and Philippe Baumer and Jacques Cosnes and Arnaud Bourreille and Jean Pierre Gendre and Philippe Seksik and Antoine Blain and Etienne Henry Metman and Andr{\'e}e Nisard and Guillaume Cadiot and Michel Veyrac and Benoit Coffin and Xavier Dray and Fabrice Carrat and Philippe Marteau}, journal={Gut}, year={2010}, volume={60}, pages={198 - 203} }
Background and aims Few studies have been conducted addressing the safety of thiopurine treatment in pregnant women with inflammatory bowel disease (IBD). The aim of this study was to evaluate the pregnancy outcome of women with IBD who have been exposed to thiopurines. Methods 215 pregnancies in 204 women were registered and documented in the CESAME cohort between May 2004 and October 2007. Physicians documented the following information from the women: last menstrual date, delivery term…
156 Citations
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The study by Coelho et al recently published in Gut aimed at evaluating pregnancy outcomes in female IBD patients treated with thiopurines, finding that there was no increase in the risks of congenital abnormalities.
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