Pregnancy outcome following use of large doses of vitamin B6 in the first trimester.

@article{Shrim2006PregnancyOF,
  title={Pregnancy outcome following use of large doses of vitamin B6 in the first trimester.},
  author={Alon Shrim and Rada Boskovic and Caroline Maltepe and Y Navios and Facundo Garc{\'i}a-Bournissen and Gideon Koren},
  journal={Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology},
  year={2006},
  volume={26 8},
  pages={749-51}
}
Vitamin B6 is often prescribed for the treatment of nausea and vomiting of pregnancy (NVP), at much higher doses than initially recommended. Large doses of vitamin B6 have been associated with cases of neuropathy. We set out to assess whether higher than standard doses of vitamin B6 during the first trimester of pregnancy were associated with a risk of maternal adverse events, major malformations, miscarriages or low birth weight. This was a prospective comparative observational study. The… CONTINUE READING

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