Pregnancy occurring during or following adjuvant trastuzumab in patients enrolled in the HERA trial (BIG 01-01)

@article{Azim2012PregnancyOD,
  title={Pregnancy occurring during or following adjuvant trastuzumab in patients enrolled in the HERA trial (BIG 01-01)},
  author={Hatem A. Azim and Otto Metzger-Filho and Evandro de Azambuja and Sibylle Loibl and Florine Focant and Ekaterina Gresko and Mounir Arfi and Martine J. Piccart-Gebhart},
  journal={Breast Cancer Research and Treatment},
  year={2012},
  volume={133},
  pages={387-391}
}
Only few case reports describe the pregnancy course and outcome of breast cancer patients, who were under treatment with trastuzumab at the time of conception or who have completed trastuzumab therapy before becoming pregnant. The HERA trial is a large phase III randomized clinical trial in which patients with early HER2-positive breast cancer were randomized to receive 1 or 2 years of trastuzumab or observation following completion of primary chemotherapy. To examine the effect of trastuzumab… CONTINUE READING
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