Pregnancy-induced decrease in the relaxant effect of terbutaline in the late-pregnant rat myometrium: role of G-protein activation and progesterone.

@article{Gspr2005PregnancyinducedDI,
  title={Pregnancy-induced decrease in the relaxant effect of terbutaline in the late-pregnant rat myometrium: role of G-protein activation and progesterone.},
  author={R{\'o}bert G{\'a}sp{\'a}r and Eszter Ducza and Attila Mih{\'a}lyi and {\'A}rp{\'a}d M{\'a}rki and Zolt{\'a}n Kolarovszki-Sipiczki and Eszter P{\'a}ldy and S{\'a}ndor Benyhe and Anna Borsodi and Imre F{\"o}ldesi and George Falkay},
  journal={Reproduction},
  year={2005},
  volume={130 1},
  pages={113-22}
}
The effectiveness of beta2-agonists in preterm delivery is reduced by several factors. The aim of this study was to determine the influence of late pregnancy in the uterus-relaxing effect of terbutaline in the rat in vitro. Rat uterine tissues from late pregnancy (days 15, 18, 20 and 22) were used. In vitro electrical field-stimulation (EFS) was used to evoke contractions. The radioligand-binding technique, reverse transcription-polymerase chain reaction and radioimmunoassay technique were used… CONTINUE READING

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