Pregnancy in cystic fibrosis. Fetal and maternal outcome.

@article{Gilljam2000PregnancyIC,
  title={Pregnancy in cystic fibrosis. Fetal and maternal outcome.},
  author={Marita Gilljam and Maria-Christina Antoniou and J. C. Shin and Annie Dupuis and M. L. Corey and Diana Elizabeth Tullis},
  journal={Chest},
  year={2000},
  volume={118 1},
  pages={
          85-91
        }
}
OBJECTIVE To assess the effect of pregnancy on pulmonary function and survival in women with cystic fibrosis (CF) and to assess the fetal outcome. DESIGN Cohort study. The data analyzed were collected from the Toronto CF database, chart review, and patient questionnaire. SETTING Tertiary-care center. PATIENTS All women with CF who, at the time of diagnosis or pregnancy, attended the Toronto Cystic Fibrosis Clinics between 1961 and 1998. RESULTS From 1963 to 1998, there were 92… 

Figures and Tables from this paper

Impact of pregnancy on women with cystic fibrosis.
TLDR
These findings suggest that, over the same time period, women with CF who become pregnant experienced similar respiratory and health trends as nonpregnant women, however, pregnant women use a greater number of therapies and receive more intense monitoring of their health.
Current pregnancy outcomes in women with cystic fibrosis.
The effect of pregnancy on survival in women with cystic fibrosis.
TLDR
Women with cystic fibrosis who became pregnant were initially healthier and had better 10-year survival rates than women with CF who did not become pregnant, and pregnancy was not harmful in any subgroup including patients with FEV(1) < 40% of predicted or diabetes mellitus.
Maternal and Perinatal Outcomes in Pregnant Women with Cystic Fibrosis.
TLDR
Pregnant women with cystic fibrosis and severe lung impairment did not present an association with spontaneous prematurity, fetal growth restriction or fetal demise, and pregnancies of women with CF are frequently complicated by REs, and this population may require hospital admission during the course of the pregnancy.
Aggressive prenatal care results in successful fetal outcomes in CF women.
  • E. Cheng, C. Goss, M. L. Aitken
  • Medicine
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
  • 2006
Pregnancy outcome in women with cystic fibrosis and poor pulmonary function.
Cystic fibrosis and pregnancy in the modern era: a case control study.
Two successful pregnancies in a woman affected by cystic fibrosis: case report and review of the literature
TLDR
Pre‐pregnant lung function as well as lung function deterioration, CF‐related diabetes mellitus and weight gain in pregnancy, are parameters to consider in the counseling about the outcome of pregnancy.
Cystic Fibrosis-Related Diabetes Mellitus and Pregnancy: A Retrospective Study
TLDR
A retrospectively review maternal and foetal outcomes of pregnancies affected by maternal CFRDM highlights the importance of good glucose control, stable cystic fibrosis before pregnancy and a multidisciplinary team approach.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 39 REFERENCES
Pregnancy and cystic fibrosis: a case-controlled study.
TLDR
Pregnancy has little adverse effect on patients with stable CF, but poor outcomes can occur in individuals with more advanced disease.
Outcome of pregnancy in women with cystic fibrosis.
TLDR
Pregnancy was well tolerated by most mothers with cystic fibrosis although those with moderate to severe lung disease (%FEV1 < 60%) before pregnancy fared worse, producing preterm infants and suffering increased loss of lung function and mortality compared with mildly affected mothers.
Cystic fibrosis in pregnancy.
  • N. Kent, D. Farquharson
  • Medicine
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • 1993
TLDR
Premature labour and delivery remain a significant risk for pregnant women with CF, contributing to a high rate of perinatal death and deteriorating pulmonary function.
Cystic Fibrosis and Pregnancy
TLDR
Maternity patients with cystic fibrosis who had 13 completed pregnancies between 1975 and 1995 were retrospectively reviewed to assess the changes in spirometry and body mass index (BMI) during pregnancy and maternal and neonatal complications and outcomes.
Pregnancy in cystic fibrosis of the pancreas.
TLDR
All of the 11 living infants in the present study were normal and showed no stigmata of cystic fibrosis.
Cystic fibrosis and pregnancy.
  • D. Geddes
  • Medicine
    Journal of the Royal Society of Medicine
  • 1992
TLDR
Pregnancy is contraindicated for CF women with raised PaCO2, and SaO2 of 90%, and cor pulmonale, and a CF woman must consider timing, family support, and genetics of the father when planning a pregnancy.
Pregnancy and Cystic Fibrosis
TLDR
It is found that pregnancy can be tolerated by the majority of cystic fibrosis patients, particularly those who are pancreatic- sufficient, and had little effect on their pulmonary and nutritional status.
[Pregnancy and delivery in cystic fibrosis].
TLDR
Important premises to the management of pregnancy and delivery in cystic fibrosis have to be adequate pre- and postpartal diagnosis and therapy of pulmonary and/or cardiac disease and careful management of nutrition, control of pancreatic insufficiency and electrolyte balance.
Pulmonary function during pregnancy in cystic fibrosis: implications for counseling.
  • S. Fiel
  • Medicine
    Current opinion in pulmonary medicine
  • 1996
TLDR
A study from the Cystic Fibrosis Foundation National Patient Registry is to identify specific indices for quantitating risks related to pregnancy for women with CF so that their physicians, with these data in hand, will be better able to counsel them.
...
1
2
3
4
...