Pregnancy complications and birth outcomes of pregnant women with urinary tract infections and related drug treatments

  title={Pregnancy complications and birth outcomes of pregnant women with urinary tract infections and related drug treatments},
  author={Ferenc B{\'a}nhidy and N{\'a}ndor {\'A}cs and Erzs{\'e}bet H. Puh{\'o} and Andrew E. Czeizel},
  journal={Scandinavian Journal of Infectious Diseases},
  pages={390 - 397}
Maternal urinary tract infections in pregnancy showed an association with a higher rate of preterm birth in previous studies. The aim of this study was to check this relationship, and in addition to evaluate the efficacy of recent medical treatments. The population-based large control (without any defects) data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities was evaluated. Of 38,151 newborn infants, 2188 (5.7%) had mothers with urinary tract infections during… 

The Risk of Preterm Birth in Low Risk Pregnant Women with Urinary Tract Infections.

Low risk women with symptomatic lower urinary tract infections during pregnancy are at increased risk of spontaneous preterm birth and an increased risk for endometritis and mastitis postpartum was found in women with symptoms of symptomaticLower urinary tract infection during pregnancy.

Maternal urinary tract infection: is it independently associated with adverse pregnancy outcome?

  • E. Mazor-DrayA. LevyF. SchlaefferE. Sheiner
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2009
Maternal UTI is independently associated with pre-term delivery, pre-eclampsia, IUGR and CD, Nevertheless, it is not associated with increased rates of perinatal mortality compared with women without UTI.

Rate of preterm births in pregnant women with common lower genital tract infection: a population-based study based on the clinical practice

  • F. BánhidyN. ÁcsE. PuhóA. Czeizel
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2009
After early diagnosis and treatment of vulvovaginitis-bacterial vaginosis, clotrimazole and ampicillin seemed to be most effective to reduce the preterm birth during the study period.


It is concluded that screening and treatment of urinary tract infection in Ardabil health service is appropriate; therefore, no change is needed for present screening or treatment processes.

Risk Indicators for Urinary Tract Infections in Low Risk Pregnancy and the Subsequent Risk of Preterm Birth

In low-risk pregnant women, risk indicators for urinary tract infections are: a history of recurrent urinary tracts infections and the presence of asymptomatic bacteriuria and the risk of preterm birth is increased in women with a urinary tract infection in this pregnancy.

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

UTIs are associated with early birth regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment, and in a population of privately insured women from Iowa.

[Prevalence and associated factors with hospitalization for treatment of urinary tract infection during pregnancy].

  • A. A. HackenhaarE. Albernaz
  • Medicine
    Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
  • 2013
The socioeconomic profile of women who required hospitalization and who did not undergo adequate screening of urinary tract infection in prenatal care, demonstrate the need of more careful attention to pregnant women with the features found.

Evaluation of feto-maternal outcomes among pregnant women with co-existence of ureteric stones and urinary tract infections

The coexistence of ureteric stones and UTIs is largely affecting pregnant population and this co-morbid condition has a significant impact on fetomaternal health.

Interventions for preventing recurrent urinary tract infection during pregnancy.

A daily dose of nitrofurantoin and close surveillance has not been shown to prevent RUTI compared with close surveillance alone, and the overall quality of evidence was very low.

Association Between Urinary Tract Infection in the First Trimester and Risk of Preeclampsia: A Case–Control Study

The results of this study showed UTI during the first trimester of pregnancy is associated with the risk of preeclampsia, and controlling and treatment of urinary infections can reduce therisk of preeClampsia in the later months.



Causes of the excessive rates of perinatal mortality and prematurity in pregnancies complicated by maternal urinary-tract infections.

  • R. Naeye
  • Medicine
    The New England journal of medicine
  • 1979
Hydramnios, amniotic-fluid bacterial infections and abruptio placentae were responsible for two thirds of the more frequent preterm deliveries in the pregnancies complicated by urinary-tract infections.

Antibiotics for asymptomatic bacteriuria in pregnancy.

  • F. Smaill
  • Medicine
    The Cochrane database of systematic reviews
  • 2001
Antibiotic treatment is effective in reducing the risk of pyelonephritis in pregnancy and an apparent reduction in preterm delivery is consistent with current theories about the role of infection in pre term birth.

Pregnancy in women with kidney disease.

The present study is organized as a joint project between three medical centers with a long-standing interest in the subject, in order to include a large number of patients originating from various types of medical practice and geographic location.

Acute Pyelonephritis in Pregnancy

The incidence of pyelonephritis has remained low in the era of routine prenatal screening for asymptomatic bacteriuria, and Gram-positive uropathogens are found more commonly as pregnancy progresses.

Validation studies of drug exposures in pregnant women

The evaluation of drug use on the basis of medically recorded prescribed drugs and/or usual recommendations produces a bias thus it is necessary to complete it with information from the patients.

Smoking and alcohol drinking during pregnancy. The reliability of retrospective maternal self-reported information.

Data of smoking and alcohol drinking were not collected for the data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996 because retrospective maternal self-reported data had low reliability.

Description and mission evaluation of the Hungarian case-control surveillance of congenital abnormalities, 1980-1996.

This system is appropriate for postmarketing the surveillance of drug teratogenicity, for the improvement of congenital abnormality diagnosis, to get informed consent, to have a communication with parents and to provide material for research.

First 25 years of the Hungarian congenital abnormality registry.

The Hungarian Congenital Abnormality Registry was established in 1962 based on obligatory notification of cases with congenital abnormalities by physicians. However, continuous and expert evaluation

Ten years of experience in periconceptional care.

  • A. Czeizel
  • Medicine
    European journal of obstetrics, gynecology, and reproductive biology
  • 1999

Bacteriuria and pyelonephritis of pregnancy.

  • E. Kass
  • Medicine
    Archives of internal medicine
  • 1960
Analysis of the bacterial colony counts of urines obtained from large numbers of patients has indicated that, except for certain defined clinical circumstances, a colony count greater than 100,000 per milliliter of freshly obtained urine generally indicates the presence of true bacteriuria.