Pregnancy complicated with Alport syndrome: a good obstetric outcome and failure to diagnose an infant born to a mother with Alport syndrome by umbilical cord immunofluorescence staining.

@article{Matsubara2009PregnancyCW,
  title={Pregnancy complicated with Alport syndrome: a good obstetric outcome and failure to diagnose an infant born to a mother with Alport syndrome by umbilical cord immunofluorescence staining.},
  author={Shigeki Matsubara and Yoshihiko Ueda and Hisako Takahashi and Takashi Nagai and Tomoyuki Kuwata and Shigeaki Muto and Takehiko Yamaguchi and Toshihiro Takizawa and Mitsuaki Suzuki},
  journal={The journal of obstetrics and gynaecology research},
  year={2009},
  volume={35 6},
  pages={1109-14}
}
Alport syndrome is a familial progressive nephritis. The most frequent type is X-linked Alport syndrome, caused by genetic abnormalities in the alpha 5 chain of type IV collagen. Skin biopsy is a useful tool for diagnosing this disease. It is not well known how this syndrome affects pregnancy and how it is affected by pregnancy, or whether the umbilical cord may provide material for detecting this collagen abnormality. We report a primigravida with Alport syndrome with mild proteinuria who gave… CONTINUE READING