Pregnancy-associated plasma protein-A (PAPP-A) and hCG in early pregnancy.

  title={Pregnancy-associated plasma protein-A (PAPP-A) and hCG in early pregnancy.},
  author={Paul Bischof and S Duberg and Walter Herrmann and Pierre C. Sizonenko},
  journal={British journal of obstetrics and gynaecology},
  volume={88 10},
Pregnancy-associated plasma protein-A (PAPP-A) is a recently described glycoprotein of unknown biological function. The development of a radioimmunoassay enabled us to measure plasma levels of PAPP-A and human chorionic gonadotrophin (hCG) in 12 non-pregnant volunteers and in 159 women in early pregnancy attending the outpatient clinic for legal abortion. PAPP-A but not hCG was measurable in all non-pregnant women. In pregnant patients (with 36 to 86 days of amenorrhea) hCG reached a peak value… CONTINUE READING

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