Pregnancy and steroid hormones enhance the systemic and regional hemodynamic effects of calcitonin gene-related peptide in rats.

@article{Gangula2001PregnancyAS,
  title={Pregnancy and steroid hormones enhance the systemic and regional hemodynamic effects of calcitonin gene-related peptide in rats.},
  author={Pandu R. R. Gangula and Huawei Zhao and Sunil J. Wimalawansa and Scott C. Supowit and Donald J Dipette and Chandrasekhar Yallampalli},
  journal={Biology of reproduction},
  year={2001},
  volume={64 6},
  pages={1776-83}
}
Calcitonin gene-related peptide (CGRP) is a potent vasodilator neuropeptide known to be involved in the regulation of vascular resistance. Several lines of evidence suggest that CGRP plays a role in the vascular adaptations that occur during normal pregnancy; however, the effects of exogenous CGRP on systemic and regional hemodynamics during pregnancy remain unknown. Therefore, the purpose of this study was to determine the hemodynamic effects of systemically administered CGRP in adult pregnant… CONTINUE READING
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