Pregnancy and fetal long-chain 3-hydroxyacyl coenzyme A dehydrogenase deficiency.

@article{Wilcken1993PregnancyAF,
  title={Pregnancy and fetal long-chain 3-hydroxyacyl coenzyme A dehydrogenase deficiency.},
  author={Bridget Wilcken and K. C. Leung and John H Hammond and Ravi Kamath and James V. Leonard},
  journal={Lancet},
  year={1993},
  volume={341 8842},
  pages={407-8}
}
We report on eleven pregnancies in 5 mothers. 6 of the babies had long-chain 3-hydroxyacyl coenzyme A dehydrogenase (LCHAD) deficiency, and each of the pregnancies was complicated by features such as fatty liver and HELLP (haemolysis, elevated liver enzymes, low platelets) syndrome. By contrast, 3 of the mothers also gave birth to unaffected babies, and these pregnancies were largely uncomplicated. We conclude that there may be adverse effects on maternal liver function from a fetus with LCHAD… CONTINUE READING

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