Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin

@article{Shingo2003PregnancyStimulatedNI,
  title={Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin},
  author={Tetsuro Shingo and Christopher Gregg and Emeka K Enwere and Hirokazu Fujikawa and Rozina Hassam and Colleen Geary and James C Cross and Samuel Weiss},
  journal={Science},
  year={2003},
  volume={299},
  pages={117 - 120}
}
Neurogenesis occurs in the olfactory system of the adult brain throughout life, in both invertebrates and vertebrates, but its physiological regulation is not understood. We show that the production of neuronal progenitors is stimulated in the forebrain subventricular zone of female mice during pregnancy and that this effect is mediated by the hormone prolactin. The progenitors then migrate to produce new olfactory interneurons, a process likely to be important for maternal behavior, because… Expand
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References

SHOWING 1-10 OF 40 REFERENCES
Neurogenesis in an adult insect brain and its hormonal control
TLDR
Undifferentiated cells are reported, located dorsally in mushroom bodies of the house cricket Acheta domesticus, that persist, divide and give rise to cortical interneurons during adult life and juvenile hormone, which induces oviposition behaviour in adult crickets, acts on neurogenesis in this cell cluster. Expand
Enriched Odor Exposure Increases the Number of Newborn Neurons in the Adult Olfactory Bulb and Improves Odor Memory
TLDR
It is shown that adult mice housed in odor-enriched cages display improved olfactory memory without a change in spatial learning performance, suggesting that ongoing bulbar neurogenesis could be associated with improved o aroma memory. Expand
Long-distance neuronal migration in the adult mammalian brain.
TLDR
Grafted and endogenous SVZ cells in the lateral ventricle of adult mice migrate long distances and differentiate into neurons in the olfactory bulb. Expand
The common properties of neurogenesis in the adult brain: from invertebrates to vertebrates.
TLDR
The common characteristics of adult neurogenesis in the various animal models studied so far are discussed and comparative study of the various model systems could contribute to better understand this phenomenon. Expand
The generation, migration, and differentiation of olfactory neurons in the adult primate brain
  • D. R. Kornack, P. Rakić
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
TLDR
Results indicate that dividing cells in the adult monkey SZ generate neuroblasts that undergo restricted chain migration over an extended distance of more than 2 cm to the OB and differentiate into granule interneurons, which support the use of the SZ/RMS as a model system for studying neural regenerative mechanisms in the human brain. Expand
From Embryo to Adult: Persistent Neurogenesis and Apoptotic Cell Death Shape the Lobster Deutocerebrum
TLDR
The results indicate that, in juvenile and adult lobsters, birth and death of olfactory interneurons occur in parallel, suggesting a turnover of these cells. Expand
Erythropoietin Regulates the In Vitro and In Vivo Production of Neuronal Progenitors by Mammalian Forebrain Neural Stem Cells
TLDR
It is found thatEPO receptors are expressed in the embryonic germinal zone during neurogenesis as well as in the adult subventricular zone, which continues to generate neurons throughout adulthood, suggesting that EPO is an autocrine–paracrine factor, capable of regulating the production of neuronal progenitor cells by forebrain NSCs. Expand
Importance of newly generated neurons in the adult olfactory bulb for odor discrimination.
TLDR
It is found that the specific reduction in the newly generated interneuron population resulted in an impairment of discrimination between odors, demonstrating that a critical number of bulbar granule cells is crucial only for odor discrimination but not for general olfactory functions. Expand
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.
TLDR
Cells of the adult mouse striatum have the capacity to divide and differentiate into neurons and astrocytes. Expand
Null mutation of the prolactin receptor gene produces a defect in maternal behavior.
TLDR
The PRLR is established as a regulator of maternal behavior in mice carrying a germ line null mutation of the PRL receptor (PRLR) gene, and eating, locomotor activity, sexual behavior, and exploration are normal in PRLR mutant mice. Expand
...
1
2
3
4
...