Pregnancy Is Associated with Decreased Cardiac Proteasome Activity and Oxidative Stress in Mice

@inproceedings{Iorga2012PregnancyIA,
  title={Pregnancy Is Associated with Decreased Cardiac Proteasome Activity and Oxidative Stress in Mice},
  author={Andrea Iorga and Shannamar Dewey and Rod Partow-Navid and Aldrin V Gomes and Mansoureh Eghbali},
  booktitle={PloS one},
  year={2012}
}
During pregnancy, the heart develops physiological hypertrophy. Proteasomal degradation has been shown to be altered in various models of pathological cardiac hypertrophy. Since the molecular signature of pregnancy-induced heart hypertrophy differs significantly from that of pathological heart hypertrophy, we investigated whether the cardiac proteasomal… CONTINUE READING