Pregnancy IFN-gamma responses to foetal alloantigens are altered by maternal allergy and gravidity status.

@article{Breckler2008PregnancyIR,
  title={Pregnancy IFN-gamma responses to foetal alloantigens are altered by maternal allergy and gravidity status.},
  author={Liza Anne Breckler and Jasmine Hale and Angie L Taylor and Janet A. Dunstan and Catherine A. Thornton and Susan L. Prescott},
  journal={Allergy},
  year={2008},
  volume={63 11},
  pages={1473-80}
}
BACKGROUND During pregnancy, variations in maternal-foetal cellular interactions may influence immune programming. This study was carried out to determine if maternal responses to foetal alloantigens are altered by maternal allergic disease and/or previous pregnancies. METHODS For this cohort study, peripheral blood was collected from allergic (n = 69) and nonallergic (n = 63) pregnant women at 20, 30, 36-week gestation and 6-week postpartum (pp). Cord blood was collected at delivery. Mixed… CONTINUE READING