Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification

@article{Handyside1990PregnanciesFB,
  title={Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification},
  author={A. Handyside and E. H. Kontogianni and K. Hardy and R. Winston},
  journal={Nature},
  year={1990},
  volume={344},
  pages={768-770}
}
  • A. Handyside, E. H. Kontogianni, +1 author R. Winston
  • Published 1990
  • Biology, Medicine
  • Nature
  • OVER 200 recessive X chromosome-linked diseases, typically affecting only hemizygous males, have been identified. In many of these, prenatal diagnosis is possible by chorion villus sampling (CVS) or amniocentesis, followed by cytogenetic, biochemical or molecular analysis of the cells recovered from the conceptus. In others, the only alternative is to determine the sex of the fetus. If the fetus is affected by the defect or is male, abortion can be offered. Diagnosis of genetic defects in… CONTINUE READING

    Paper Mentions

    OBSERVATIONAL CLINICAL TRIAL
    Records of women who had Pre-genetic diagnosis (PGD) over the last 3 years will be reviewed and its outcome will be compared to other records of women who had IVF/ICSI without PGD.  
    ConditionsPregnancy
    InterventionGenetic
    Preimplantation genetic diagnosis: state of the art.
    • 200
    Preimplantation genetic diagnosis
    • 340
    • Open Access

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