Pregnancies following blastocyst stage transfer in PGD cycles at risk for beta-thalassaemic haemoglobinopathies.

@article{Palmer2002PregnanciesFB,
  title={Pregnancies following blastocyst stage transfer in PGD cycles at risk for beta-thalassaemic haemoglobinopathies.},
  author={Glenn A. Palmer and J Traeger-Synodinos and Stephen Davies and Maria Tzetis and Christina Vrettou and Minas Mastrominas and Emmanuel Kanavakis},
  journal={Human reproduction},
  year={2002},
  volume={17 1},
  pages={25-31}
}
BACKGROUND Preimplantation genetic diagnosis (PGD) usually involves blastomere biopsy 3 days post-insemination (p.i.), followed by genetic analysis and transfer of unaffected embryos later on day 3 or 4. We evaluate a strategy involving embryo biopsy on day 3 p.i., genetic analysis on day 4 and, following culture in blastocyst sequential media, transfer of unaffected embryos on day 5 p.i. METHODS PGD cycles were initiated in 15 couples at risk of transmitting beta-thalassaemia major. Oocyte… CONTINUE READING