Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte

@article{Palermo1992PregnanciesAI,
  title={Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte},
  author={Gianpiero D. Palermo and Hubert Joris and Paul Devroey and Andr{\'e} C. Van Steirteghem},
  journal={The Lancet},
  year={1992},
  volume={340},
  pages={17-18}
}
Intracytoplasmic sperm injection (ICSI) is a promising assisted-fertilisation technique that may benefit women who have not become pregnant by in-vitro fertilisation (IVF) or subzonal insemination (SUZI) of oocytes. We have used ICSI to treat couples with infertility because of severely impaired sperm characteristics, and in whom IVF and SUZI had failed. Direct injection of a single spermatozoon into the ooplasm was done in 47 metaphase-II oocytes: 38 oocytes remained intact after injection, 31… Expand

Paper Mentions

Interventional Clinical Trial
Over recent decades, the use of intracytoplasmic sperm injection (ICSI) has increased, even among patients without severe male factor infertility. Despite the increasing use, there is… Expand
ConditionsInfertility
InterventionProcedure
Interventional Clinical Trial
The use of Intracytoplasmic sperm injection (ICSI) has increased in the last decades regardless of the cause of infertility. Despite the increased use there is no clear evidence… Expand
ConditionsInfertility, Female
InterventionOther
Observational Clinical Trial
babies of known gender born out of 388 ICSI cycles were investigated for the gender ratio and then divided into three groups according to the sperm selection technique used before… Expand
ConditionsGender Ratio of ICSI Outcome
InterventionDevice, Other
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Different aspects of these novel assisted fertilization procedures are described: patient management, ovarian stimulation, semen evaluation and treatment, oocyte collection and preparation, SUZI and ICSI techniques, assessment of fertilization and embryo cleavage, outcome of embryo transfers and the evolution of the pregnancies. Expand
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A follow-up of the children born after ICSI treatment was conducted to address concerns as to the risk of transmitting genetic defects to the offspring. Expand
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ICSI has greatly improved the ability to use IVF for treating couples with a poor fertilization potential, and ICSI reinsemination was used with limited success to rescue failed fertilization cycles, although the implantation rate per embryo was poor. Expand
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The results of 600 consecutive treatment cycles of subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) are described in couples with failed fertilization after standard IVF or insufficient spermatozoa in the ejaculate for IVF to indicate an increase in congenital malformations. Expand
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Intracytoplasmic sperm injection (ICSI) is the latest, and by far the most efficient, variant of micromanipulation-assisted fertilization, whereby a single spermatozoon is selected, aspirated into aExpand
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A live piglet derived from an embryo produced by intracytoplasmic sperm injection and carried to term was born to a mother that had received 32 embryos and was underweight, though healthy and lively. Expand
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PREGNANCY AFTER TRANSFER OF SPERM UNDER ZONA