Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial.

@article{Lesser2004PregabalinRS,
  title={Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial.},
  author={Herr Dr. Lesser and Uma Sharma and Linda Lamoreaux and Raewyn M. Poole},
  journal={Neurology},
  year={2004},
  volume={63 11},
  pages={2104-10}
}
OBJECTIVE Pregabalin, an alpha2-delta ligand with analgesic, anxiolytic, and anticonvulsant activity, has been evaluated for treatment of neuropathic pain. The authors assessed the efficacy and tolerability of pregabalin (75, 300, 600 mg/day) vs placebo in patients with diabetic peripheral neuropathy (DPN). METHODS Patients with a 1- to 5-year history of DPN and average weekly pain score of > or =4 on an 11-point numeric pain-rating scale were enrolled in a 5-week, double-blind, multicenter… CONTINUE READING
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