Prefronto-striatal physiology is associated with schizotypy and is modulated by a functional variant of DRD2

Abstract

"Schizotypy" is a latent organization of personality related to the genetic risk for schizophrenia. Some evidence suggests that schizophrenia and schizotypy share some biological features, including a link to dopaminergic D2 receptor signaling. A polymorphism in the D2 gene (DRD2 rs1076560, guanine > thymine (G > T)) has been associated with the D2 short… (More)
DOI: 10.3389/fnbeh.2014.00235

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